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Nursing School3 min read

HESI Chemistry Basics for Every Nursing Student to Know

N
Naxles TeamJuly 26, 2026
HESI Chemistry Basics for Every Nursing Student to Know

Why Is Chemistry Important on the HESI EXAM?

Basic chemistry knowledge will help you understand important concepts in nursing such as pharmacology, fluid and electrolyte balance, and drug interactions in the body. A good background in chemistry now makes many of the future nursing classes much easier to understand.

Core Concept 1 Atomic Structure

Understanding the basic building blocks of matter is important for almost every other topic in chemistry.

Core Concept 2: The Basics of the Periodic Table

You do not have to memorize the whole periodic table, but it helps to know how it is laid out.

Core Concept 3: Chemical Bonding

Knowing how atoms bond together explains how molecules form and interact.

Core Concept 4: Acids, Bases, and pH

This is particularly relevant to healthcare because the body has a very specific pH balance.

Core Concept 5: Solutions, Concentration, and Dilution

These concepts tie directly into dosage calculations that you will encounter later on the HESI exam.

How to Study Chemistry Well

Common Mistakes to Avoid

Concluding Words

You do not need to memorize all of college-level chemistry to do well on the HESI exam, but you do need to understand the basic concepts that are directly related to healthcare and nursing practice. You can streamline your review process by focusing on atomic structure, chemical bonds, pH balance, and basic solution concepts rather than feeling overwhelmed by the subject. This basic knowledge of chemistry will also help you in pharmacology and other science-based courses throughout your nursing education.

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