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HESI A2 Vocabulary: Prefixes, Suffixes, and Roots

N
Naxles TeamOctober 7, 2026
HESI A2 Vocabulary: Prefixes, Suffixes, and Roots

Using Word Parts to Improve HESI A2 Vocabulary

Vocabulary questions can become challenging when you encounter a word you have never seen before. One useful strategy is learning how words are built. Prefixes, suffixes, and roots can provide clues about meaning.

What Is a Prefix?

A prefix is a word part added to the beginning of a word. Examples include: pre- = before post- = after anti- = against sub- = under re- = again For example, “preoperative” contains pre-, suggesting something that occurs before an operation.

What Is a Suffix?

A suffix appears at the end of a word. Examples include:

Recognizing these endings can provide useful clues when encountering unfamiliar terminology.

What Is a Root?

A word root carries an important part of a word's meaning. For example, cardi is associated with the heart. Words such as “cardiology” and “cardiac” contain related word elements.

Break Unfamiliar Words Apart

Suppose you encounter an unfamiliar word. Instead of immediately guessing, look for recognizable pieces. Ask:

This method does not guarantee the correct definition, but it can provide a useful clue.

Build a Vocabulary Notebook

Create three columns:

Prefix/Root/Suffix Meaning Example pre- before prenatal anti- against antibiotic -itis inflammation arthritis cardi- heart cardiac Review a few entries each day rather than trying to memorize a large list at once.

Final Takeaway

Learning word parts can make unfamiliar HESI A2 vocabulary less intimidating. Build your knowledge of common prefixes, suffixes, and roots, then practice using context to determine meaning.

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