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Nursing School3 min read

100 Words You Need to Know HESI Vocabulary List

N
Naxles TeamJuly 26, 2026
100 Words You Need to Know HESI Vocabulary List

Why Vocabulary is Important on the HESI Exam

Vocabulary questions usually test your ability to infer the meaning of words in isolation and in context, often drawing on general academic language and basic medical terminology. These skills will also help you on the reading comprehension section of the test. Unfamiliar words can slow you down or confuse your understanding of an entire passage.

Medical Root Words and Prefixes (25 Terms)

In addition, even if you have not memorized a specific word before, knowing common medical prefixes and roots can help you figure out unfamiliar terms. Cardio- , Hepato- , Nephro- , Gastro- , Neuro- , Dermato- , Osteo- , Hemo- , Pulmo- , Cyto- , -itis , -ology , -ectomy , -otomy , -pathy , -algia , -emia , -uria , Brady- , Tachy- , Hyper- , Hypo- , Peri- , Sub- , Inter-

Medical Terms (25 Words) Common

These words are commonly seen in medical vocabulary sections and reading passages on healthcare topics.

Diagnosis Prognosis Chronic Acute Benign Malignant Contraindication Prescription Symptom Syndrome Pathogen Antibiotic Inflammation Infection Immunity Homeostasis Metabolism Ventilation Circulation Respiration Digestion Excretion Secretion Absorption Contraction

General Academic Vocabulary (25 Words)

In addition to medical terminology, the HESI vocabulary section also covers general academic and everyday words found in reading passages.

Ambiguous, Short, Resulting, Decrease, Ease, Wave, Assumption, Implied, Inevitable, Careful, Remark, Neutral, Plausible, Previous, Predominant, Common, Reason, Important, Following, Enough, Sensitive, Preliminary, Fundamental, Changeable, Confirm

Commonly Confused or Misused Words (25 Words)

They are easily confused with words that look or sound alike, so these are frequently tested words.

How to Learn Vocabulary like a Pro

Tips to Remember Difficult Words

In conclusion

There is not one vocabulary list that will cover every word that you will see on the HESI, but if you focus your study on high frequency medical terms, general academic vocabulary and frequently confused pairs of words, you will build a solid, focused base. Rather than attempting to memorize an overwhelming number of random words, use this organized list as a starting point, and review it consistently in small, manageable sections. A strong vocabulary will not only help you with this one section, but it will also help you with the rest of the exam and your nursing education in general.

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